Additional Benefits of Anti-GIP mAb

• Decreased fat deposition everywhere (abdominal cavity, liver, skin)
• Type 2 diabetes developed in the untreated animals, but not in those treated with the Anti-GIP mAb
• The lipid profile of the treated mice was normal
• Triglycerides decreased
• Total cholesterol decreased
• Low-density lipoproteins (“bad cholesterol”) decreased
• High-density lipoprotein (“good cholesterol”) ratio increased