For more information behind the science of Lobesity, please refer to these research studies:
Tseng, CC, Kieffer, TJ, Jarboe, LA, Usdin, TB, and Wolfe MM. “Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat.” J Clin Invest 98, vol. 11 (Dec 1996): 2440-2445.
Miyawaki K, Yamada Y, Ban N, Ihara Y, Tsukiyama K, Zhou H, Fujimoto S, Oku A, Tsuda K, Toyokuni S, Hiai H, Mizunoya W, Fushiki T, Holst JJ, Makino M, Tashita A, Kobara Y, Tsubamoto Y, Jinnouchi T, Jomori T, Seino Y. “Inhibition of gastric inhibitory polypeptide signaling prevents obesity. “ Nat Med 8, vol. 7 (Jul 2002): 738-742.
Boylan MO, Glazebrook PA, Tatalovic M, Wolfe MM. “Gastric inhibitory polypeptide immunoneutralization attenuates development of obesity in mice.“ Am J Physiol Endocrinol Metab 309, vol. 12 (Dec 2015): 1008-1018.
Zhang CY, Boylan MO, Arakawa H, Wolfe MM. “Effects of gastric inhibitory polypeptide (GIP) immunoneutralization on mouse motor coordination and memory” Peptides 2019 Dec 2:170227. doi: 10.1016/j.peptides.2019.